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Safety Data Sheet <br />_____________________________________________________________________________________________ <br />MethanolNAGH/EN <br />Product name <br />80056Oct.07.2015 <br />MSDS numberRevision Date <br />0Oct.07.2015 <br />Revision NumberIssuing date <br />_____________________________________________________________________________________________ <br />May be fatal if swallowed. A small amount of Methanol (usually two or more ounces) <br />Ingestion <br />can cause mental sluggishness, nausea and vomiting leading to severe illness, and <br />may produce adverse effects on vision with possible blindness or death if treatment <br />is not received. <br />Overexposure (prolonged or repeated exposure) may cause: <br />Target organ effects <br />Central nervous system depression <br />Injury to the eyes <br />Drying of the skin <br />Local irritation at the site of exposure <br />Significant exposure to this chemical may adversely affect people with acute or <br />Medical conditions which may be <br />chronic disease of the: <br />aggravated by exposure: <br />Skin <br />Eyes <br />Central nervous system <br />Digestive tract <br />Methanol <br />LD50: > 5000 mg/kg <br />Acute oral toxicity <br />LD50: > 5000 mg/kg <br />Acute dermal toxicity <br />LC50 (4h): > 5 mg/l <br />Acute inhalation toxicity <br />irritating <br />Skin corrosion/irritation <br />nonsensitizer <br />Skin Sensitization <br />Speciesguinea pig <br />MethodMaximization <br />irritant <br />Serious eye damage/eye irritation <br />Speciesrabbit eye <br />No evidence of carcinogenicity <br />Carcinogenic effects <br />Speciesrats <br />Studyinhalation lifetime study <br />No evidence of carcinogenicity <br />Carcinogenic Effects <br />Speciesmice <br />Studyinhalation lifetime study <br />Ames Test: negative - with and without metabolic activation - <br />in vitro Mutagenicity <br />Method: OECD 471 Mouse lymphoma cell gene-mutation: <br />positive - with and without metabolic activation - Method: <br />OECD 476 In vitro Sister Chromatid Exchange Assay in <br />Chinese Hamster Ovary (CHO): negative - with and without <br />metabolic activation - Method: OECD 479 In vitro <br />Mammalian Cell Transformation Test: negative - without <br />metabolic activation - EU-Method: B.21 <br />Positive and negative results <br />in vivo Mutagenicity <br />Reproductive toxicity Some indication of reproductive toxicity in animals at non- <br />physiological levels <br /> 7 of 10 <br /> <br />