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<br />
<br />C,
<br />
<br />Medrol®
<br />brand of methylprednisolone tablets
<br />For Oral Use-In Doga and Cats
<br />INDIGTIONS: The indiations ter MEDROL Tahbts are Ne soma u Nose for
<br />etlter ami-inflamrtutory steroMs aiM comprise Ire r+rious collagen, dermal.
<br />allergic,Qatar, otie. and musaloskeletal armillom known ro De responsive to
<br />the ami-imlammatorymrDrostemids. HeGpresentaUre of the cortdidons in wnicn
<br />Ne use of steroid ttcenq arm Ne benefits to De derived Nerefrom hero had
<br />repeated cenfumaDOn in the vetennary litenture an: (t) dermal cendlDons
<br />such anon-spedfit eczema. summer dertnaDtls, and bums; (2) afteryic man-
<br />gestaDOnA sudt tie ante urtiaria, allergic dermatitlR drug and serum reac-
<br />Dons. btondtial astMna.and pollen semRMtles; (3) otifu anddlom, such as
<br />iritis, iridocyclitc, seeamary glauama, ureitis antl thorroretlnitis: (4) a3e
<br />armitiats. sttdr u miDs extema; (5) musaloskeleW cortONons, wcn as myo-
<br />sltls, Ntimatoid aruuitis, osteoartAritls, and Dursdh; (6) various chronic or
<br />reanem tlLuases of unknown etiology wcn as ulcenDro colitis and nepAroste.
<br />CONTNAINOICATtONS: YEDROLTaDIdslike prednisobne,are antraindicated to
<br />animals with arrested tuberculosis, Geytic ulcer, acute psychoses, and
<br />Cushimloid syndrome TAe presence of d'wDdes osteoporosis, cAroac psy-
<br />tAotk reachorrs D onto NromhoDhleMtls, nypertensron, angutM
<br />mart failure, renal i ~ ficm' nry, atM adM tuberaiosis necessitates antuly
<br />ConDOlled use Soma of the zboro tond'Nom ottir Dory every in dogs afro tits
<br />but sooum De kept N oiled.
<br />CAUTIONS: Because of its iMibitory efled on fiDroplasia. methylprednisolom
<br />may mask Na signs of intettfons and enhance dlsseminaaon of the trtfedinq
<br />agaasm Henn. >U anurul paDems reaivina medhylprednisolone snoum Da
<br />waWed for evidence at intercunem infection. Should intection occur, H must De
<br />brought under ceMd Dy use m appropprinate amlDaderial measures, or adminis-
<br />traDon of metlp4pretlresobne should Oe discentlnued.
<br />YYanlog: Not for human use. CSniW and experimemal don nave demonstrated
<br />OW tinicesteroids administered Dotty or parentenlly to animals may induce
<br />Ne first sage of parturDmn when admimsteretl dunnp Ne Wst trimester o1
<br />~ ~~a ate~~roreD~rrodntollowedbydygtocia,fetel
<br />Addi0onaly, certlcesteroids adMnistered to dogs, rabbits and rodents during
<br />pprretgqnanLy bare rewlbm in den Dalate in oflsprinq. Cortcosteroids admin-
<br />i50ered ro dogs durirp pregnartcy hero alw resulted m other congenital artonta-
<br />Iles indrminq nfelame0 rorekgA Dhocomelu, arm anasata.
<br />PNECAtRI0N3: YEDROL TaWate, like ptednisolorro and otAer atlrenocortlal
<br />rietoids b s potent thdapeuDC apem mlNenemp Na Oirkhemial Oehavior of
<br />most. H not all. tissue of Dte body. Beause Ihls amHmlammatory steroid
<br />manAesb little sodium-retaining 1X, Ne usual sorry sign m nxtrDSOne or
<br />rou~rdhbleDeidenalovwdosag~ie.Hencernrecommo deddoufiubvel5s~oulnlnoLt
<br />De ntxaeded, and all animal patiems reaivirp MEOROL mould Da under dose
<br />medical wperrisioe M~,~tl ors peNnent to the use of pnvAnisolone appty
<br />to metlrylpretlmwlare 4oreOror, Ne vaterutarian should endeavor ro keep
<br />inlortned of tirrem sttmies wiN MEDRDL as they ua reported m the veterinary
<br />fiterarone.
<br />AOYENSE iIFJlCTi01B: WM therapeutlWty equivalent doses, Ne OkeliAaod at
<br />otxanrrence al troublesome side eNeds is kss with maU~prednisolone tAan
<br />wiN pretlnisolone: ooreoror, side effects actualty have been consplaotnsry
<br />aDSem during diniW Dials wUh MEOROL Tablets in dogs and Ws flowerer,
<br />metlrylpretltisolan is smiw ro prednlsolone in negam ro kmds of side eDeds
<br />and mnteDOtlc altnxmom ro De amuJpated wAen treatment b Intemire or D~
<br />taped. In adrttal patiads aidt diabetes mellitus, use of methylprednisolone
<br />may be associated wile m inaease m Ne insulin requirement. Negative nnbogen
<br />balance may otar, IarDadarly te animals teat regare protruded maintenance
<br />tnerapy; measmes ro camteract persistent nitrogen loss induce a Aiph protein
<br />htteka and Ne admmnstration when IndlatW, of a swtaDle ana~olic~appent.
<br />Fxceuive kw of potassium like excessive netaniDon of wdlum. is not 0kery ro
<br />De kmuad by eRecDre mainteruna doses o1 MEDRDL. However, Nese efects
<br />sAtild De keW ai mood antl the tatial raqulatory meawres emWoyed as indi-
<br />cted, manEateDOns,nvhilenotnoleddunngtAedin enlwDon
<br />in dops~may nxar. It wch reactions do ottir and are serious, redue-
<br />Don N dosage a dLUnriDnuarrce of methylpednisodne Nappy may De intli-
<br />Wed.Continent use d daityoret suDDlements of ascorbic add may De of value
<br />N Relpinp ro ceritrd etchymotk tandancias.
<br />Since metlrylptedrrisdlone. )Ore prnbtriwlorm, wpDresses endoperrous adreno-
<br />tortiW arsivity. N b tagAy unpovlartt tAat Ne animal patient nxerrinp MED30L
<br />Da undo Wehd adSerraDOn. na Dory durAry Ne nxwrse of hvabnen! Dut !or
<br />soma tlme alts treatrarttn terminated. Adequate adrenommW supportive
<br />witA cortlsont orl~~drocortlsone, and lndudup ACiH, mus! De am-
<br />promp~ arnnraliswDlxtedtoarryunusualsAesssuchassurpery,
<br />ADMINISTNATION:The keyslate m satistadory Nenpautlc mariagemem wcn
<br />MEOROL Tahleh, as wiN ds steroid predecessors. is lndivmt¢I¢aDOn of dosage
<br />in reterena ro the serWy, dl the disease. Ne anDdpated dunfion of sterend
<br />Narapy, and Ne iniml patxm's threshold or rolennce for steroid excess The
<br />prime oDlxuw of ddoid NenDy sodum be to atAiere a satisfadory degree of
<br />control wnh a minmunn ettediro daily dose.
<br />me dosage raammadaDora an wgppested Deeps mhl da/ry doasa and are
<br />intended as aides. As wiDt other onlh(administerM certicosteronds Ne total
<br />dairy doss of MEDROt shadd De given m squatty divided doses
<br />The maimenance dose level should be adjusted from time ro Gros u required by
<br />SuduaDon ro Gut acDrdy of Ne disease and tAe animal's general stetus Aau-
<br />mulated experience AaS mown that Ne lonq•term benefits to DB gained Irom
<br />nxmDiluetl sterom maimmarna are proDa0ry greater the lower fire maudenana
<br />dou lend.
<br />D08AGE: Avenge Mtal6adr on/ doses ror dogs and tits ue u tolWrs:
<br />5 ro 15 ID DOttI' wt ......... 2 mq 40 ro 80 W body wt ... 4 to 8 nip
<br />15ro4DIDDoilywt ..... 2ro4mq
<br />The rorv dairy dose shouts be given in diridetl doses. 6 ro 10 Mars apart
<br />HO1N SUPPLI W: Veterinary YEOROL Tablets an compressed wss-store0
<br />teDkb avaitabkt is the fdbvrinq strengtAs: t mq -Bottles of 2000:
<br />NOC 0009-0597-0/. l aq - Bomes of 500: NOC 0009354).01.
<br />Fun I mq teDk1 nxurtaim t nip metnylpednisolone and each 4 nip nDld cen-
<br />teim 4 mq medrylpnt#naaom.
<br />CasDeo: Federal (USA) taw restricts Nis drug ro use try er on Ne oroer of a
<br />)lamed vetednarwi
<br />IDs Uplo4a Compaq • Katania:oo, Midipan 49001. USA 312 6D2104
<br />Revised FaDnuty 1990 ~ 690305
<br />Your Solution Sources
<br />The Upjohn Company, Animal Health Division
<br />Kalamazoo, MI 49001
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<br />SYMPOSIUM ON POTBELLIED PIGS
<br />Raising a healthy potbellied pig (conYd)
<br />Also, dogs are known to eat both ca-
<br />nine and feline feces, which may
<br />fizrther expose them to disease.
<br />Some diarrheal diseases of hu-
<br />mans, such as salmonellosis and
<br />campylobacteriosis, may be trans-
<br />mitted from the pet pig. But the
<br />risk of this happening is no greater
<br />than the risk of transfer of the same
<br />infections from dogs or cats. Dogs
<br />or cats may carry vectors (e.g. fleas
<br />or ticks) of certain diseases such as
<br />borreliosis (Lyme disease), tu-
<br />laremia, plague, or typhus. Pigs do
<br />not harbor these vectors and there-
<br />fore are not involved in the trans-
<br />mission of these diseases to people.
<br />Other diseases are cat- and dog-spe-
<br />cific, such as hydatid disease, cat
<br />scratch fever, and hookworm infec-
<br />tion. Though both pigs and cats can
<br />have toxoplasmosis, only the cat
<br />will transmit the disease to people
<br />through afecal-oral route. The only
<br />way a pig can transmit toxoplasmo-
<br />sis is through the human consump-
<br />tion of undercooked pork that has
<br />the tissue cysts of toxoplasmosis,
<br />something not contemplated for the
<br />Pet pig.
<br />Rabies is always a serious con-
<br />cern for pet owners. Most local or
<br />state governments require the vac-
<br />cination of dogs and cats against ra-
<br />bies. These pets may acquire the
<br />disease from other infected pets or
<br />from infected wildlife such as bats,
<br />skunks, or raccoons. Though the pig
<br />has the potential to become infected
<br />q$,8 VETERINARY MEfACWE/MAY 1993
<br />by the rabies virus, the porcine
<br />species is very resistant to infec-
<br />tion. In contrast to the hundreds of
<br />cases of rabies in cats, dogs, and
<br />wildlife reported each year, only
<br />one or two cases of swine rabies are
<br />reported °~ Moreover, these cases
<br />are in commercial swine herds; none
<br />has been reported in potbellied
<br />pigs. Pigs have never been linked to
<br />human rabies infection in the
<br />United States.
<br />Conclusion
<br />With sufficient knowledge of the re-
<br />quirements of the potbellied pig,
<br />veterinarians can assist their clients
<br />in the proper rearing and hus-
<br />bandry of these new pets. This arti-
<br />cle presents the information needed
<br />for the small-animal practitioner to
<br />feel more comfortable working with
<br />these patients.
<br />REFERENCES
<br />1. Reeves, D.: Neonatal Care of Miniature Pet Pigs.
<br />GuideCmes ltx the Veterinary PracMioner Cale and
<br />Mark current of Miniature Pet Pigs (D. Reeves, ed.).
<br />Veterinary Practice Publishing Co., Santa Barbara,
<br />Calif., 1993: PP 41-45.
<br />2. Cowart, R.P: Hypoglycemia and Hypothermia in
<br />Neonatal Pigs. Currant Veterinary Therapy Food Ani-
<br />mel Practice, 3rd Ed. (J. Howard, ed.). W.B. Saun-
<br />ders. Philadelphia, Pa., 1993; PP 119-120.
<br />3. Dorfman, B.: The Miniature Potbelly Pig as a
<br />House Pet: A Comparison with Cats and Dogs. Poi-
<br />ihelly Pig Press, Gtrb Cochon Newsletter, Grass Val-
<br />ley, Catrf., Summer 1991; pp 2-4.
<br />4. Reid-Sander, F.L et al: Rabies Surveillance in the
<br />United States During 1989. JAIAIM 197:1571-1583;
<br />1990.
<br />5. Uht9a, I.J. et al: Rabies Stuveillance in the United
<br />States During 1990. JAVMA 200:920.929; 1992.
<br />6. Krebs, J.W. et al: Rabies Surveillance in the
<br />United States During 1991. JAVMA 201:183Er1848;
<br />1992.
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